Not merely its total but in addition the functional Homes of Hb have an impact on effectiveness. That is illustrated via the observation that an increased Hb-O2 affinity favors O2 loading inside the lung and survival in an hypoxic environment (Eaton et al., 1974; Hebbel et al., 1978), whereas a decreased Hb-O2 affinity favors the release of O2 with
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